5-Amino-1MQ (5-Amino-1-Methylquinolinium) is a small molecule that selectively inhibits nicotinamide N-methyltransferase (NNMT). Research has shown its potential in regulating cellular energy expenditure and metabolic pathways.
Required to reconstitute lyophilized peptides before use in research.
Key findings from published peer-reviewed research studies.
Disclaimer: This product is intended for research use only. Not for human consumption, therapeutic use, or diagnostic purposes.
| Chemical Name | 5-Amino-1-methylquinolinium chloride |
| CAS Number | 352030-82-1 |
| Molecular Formula | C₁₀H₁₁ClN₂ |
| Molecular Weight | 194.66 g/mol |
| Type | Small molecule NNMT inhibitor |
| Target | Nicotinamide N-methyltransferase (NNMT) |
| Mechanism | Competitive NNMT inhibitor, increases NAD+ via salvage pathway |
| Appearance | White to off-white crystalline powder |
| Purity | ≥99% (HPLC) |
| Solubility | Soluble in water and DMSO |
5-Amino-1MQ is a selective small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that plays a key role in cellular energy metabolism and has been linked to obesity and metabolic dysfunction.
NNMT methylates nicotinamide using SAM as a methyl donor. Inhibiting NNMT increases both NAD+ (from salvaged nicotinamide) and SAM levels, boosting cellular energy metabolism and epigenetic regulation.
No, 5-Amino-1MQ is a small molecule compound, not a peptide. It is a quinolinium derivative with a molecular weight of only 194.66 g/mol, making it much smaller than peptides.
Store the dry powder at -20°C in a sealed container protected from moisture and light. It can be dissolved in water or DMSO for research applications.
Peer-reviewed publications and reference materials.
Our products are strictly intended for laboratory research use only. Not for human or animal consumption. By purchasing, you confirm that you are a licensed researcher or purchasing for research purposes.
