Required to reconstitute lyophilized peptides before use in research.
MOLECULAR WEIGHT
Daltons
AMINO ACIDS
Peptide sequence
STUDIES
Published research
PURITY
HPLC verified
Key findings from published peer-reviewed research studies.
Published Studies
Wound Closure Rate
Peptide Sequence
Faster Recovery
Significantly accelerated wound closure in dermal injury models
Studies demonstrated TB-500 promoted cell migration, angiogenesis, and collagen deposition, resulting in faster tissue repair compared to control groups.
Improved cardiac function after ischemic injury in preclinical models
Research showed upregulation of Akt signaling pathway and enhanced cardiomyocyte survival, leading to improved left ventricular function post-injury.
Reduced inflammatory markers in multiple tissue types
TB-500 demonstrated suppression of NF-κB activation and reduced production of pro-inflammatory cytokines including TNF-α and IL-6.
Enhanced neural recovery and reduced neuroinflammation
Preclinical data suggests TB-500 supports oligodendrocyte differentiation and promotes remyelination in central nervous system injury models.
Organ Toxicity
Shelf Stability
Therapeutic Index
No significant adverse effects observed at standard research dosages in preclinical studies.
Extended administration studies showed no organ toxicity or significant changes in hematological parameters.
No known interactions reported in published literature. Consult research protocols for combination studies.
Lyophilized powder stable for 24+ months at -20°C. Reconstituted solution stable for up to 30 days at 2-8°C.
Research use only. Not for human consumption. Should not be used in subjects with known hypersensitivity to any component.
Disclaimer: This product is intended for research use only. Not for human consumption, therapeutic use, or diagnostic purposes.
4,963 Da
43
≥99%
<0.1 EU/mg
| Chemical Name | Thymosin Beta-4 Fragment (17-23) |
| CAS Number | 77591-33-4 |
| Molecular Formula | C₂₁₂H₃₅₀N₅₆O₇₈S |
| Molecular Weight | 4,963.44 g/mol |
| Sequence | Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in sterile water, bacteriostatic water |
| Purity | ≥99% (HPLC) |
| Counter Ion | Acetate (TFA-free) |
| Endotoxin Level | <0.1 EU/mg |
TB-500 is a synthetic version of the naturally occurring 43-amino acid peptide thymosin beta-4 (Tβ4). It is one of the most abundant intracellular proteins and plays a critical role in tissue protection, repair, and regeneration.
Store lyophilized TB-500 at -20°C for long-term storage. Once reconstituted, store at 2-8°C and use within 30 days. Avoid repeated freeze-thaw cycles.
Reconstitute with bacteriostatic water by gently injecting the solvent into the vial along the side wall. Allow the peptide to dissolve naturally without shaking or vortexing.
TB-500 is a synthetic analog of the active region of thymosin beta-4. While structurally similar, TB-500 is specifically designed for research applications with optimized stability and purity.
Every batch undergoes HPLC analysis for purity verification, mass spectrometry for identity confirmation, endotoxin testing (LAL), sterility testing, and amino acid analysis.
Peer-reviewed publications and reference materials.
Malinda KM, Sidhu GS, et al.
Journal of Investigative Dermatology (1999)
Goldstein AL, Hannappel E, et al.
Annals of the New York Academy of Sciences (2012)
Our products are strictly intended for laboratory research use only. Not for human or animal consumption. By purchasing, you confirm that you are a licensed researcher or purchasing for research purposes.