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BPC-157
BPC-157 - Image 2

BPC-157

(176 reviews)

⭐ See Our ReviewsPilot Profile
Cytoprotection Cytoprotective Mechanisms Pentadecapeptide
BPC-157 is a synthetic pentadecapeptide derived from a partial sequence of human gastric juice protein. It has been extensively studied for its cytoprotective and regenerative properties in various tissue types.
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1,419

MOLECULAR WEIGHT

Daltons

15

AMINO ACIDS

Peptide sequence

1,500+

STUDIES

Published research

99%+

PURITY

HPLC verified

  • Molecular Formula: C₆₂H₉₈N₁₆O₂₂
  • Molecular Weight: 1,419.53 g/mol
  • Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
  • Appearance: White lyophilized powder
  • Storage: Store at -20°C
  • Research Use Only
  • Clinical Research Results

Key findings from published peer-reviewed research studies.

1,500+

Published Studies

15aa

Pentadecapeptide

No LD50

Exceptional Safety

GI+

Gastroprotective

Gastrointestinal Healing

Accelerated healing of gastric ulcers and intestinal damage

BPC-157 demonstrated remarkable gastroprotective effects in multiple models including ulcers, fistulas, and inflammatory bowel conditions, with mechanisms involving NO system modulation.

Tendon & Ligament Repair

Enhanced tendon-to-bone healing in preclinical models

Studies showed BPC-157 promoted fibroblast outgrowth, collagen organization, and accelerated the recovery of transected tendons, including Achilles tendon models.

Neuroprotective Effects

Protective effects in traumatic brain injury and peripheral nerve damage

Research demonstrated BPC-157’s ability to counteract dopaminergic system disturbances and promote nerve regeneration following crush injuries.

Cytoprotective Mechanisms

Broad cytoprotection via NO system and growth factor modulation

BPC-157 interacts with the NO system, upregulates growth factor receptors (VEGFR2, EGFR), and modulates multiple protective pathways simultaneously.

  • Safety Profile
Safety information based on available preclinical and clinical data.

No

Organ Toxicity

Wide

Therapeutic Index

24+mo

Shelf Stability

Toxicity Profile

Extremely wide therapeutic index with no LD50 reached in animal studies even at very high doses. No organ toxicity observed.

Chronic Administration

Long-term studies showed no adverse effects on organ function, hematological parameters, or body weight.

Drug Interactions

BPC-157 has shown modulatory effects with various drugs including NSAIDs, alcohol, and dopaminergic agents without adverse interactions.

Storage Stability

Lyophilized powder stable for 24+ months at -20°C. Reconstituted solution stable for up to 14 days at 2-8°C.

Contraindications

Research use only. Not for human consumption. Standard peptide handling precautions apply.

Disclaimer: This product is intended for research use only. Not for human consumption, therapeutic use, or diagnostic purposes.

  • Compound Information
Detailed chemical and physical properties.
MW

1,420 Da

Amino Acids

15

Purity

≥99%

Endotoxin

<0.1 EU/mg

Chemical Name Body Protection Compound-157
CAS Number 137525-51-0
Molecular Formula C₆₂H₉₈N₁₆O₂₂
Molecular Weight 1,419.53 g/mol
Sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Peptide Length 15 amino acids
Origin Derived from human gastric juice protein BPC
Appearance White lyophilized powder
Purity ≥99% (HPLC)
Endotoxin Level <0.1 EU/mg
  • Frequently Asked Questions
Common questions about Tirzepatide.

What is BPC-157?

BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide consisting of 15 amino acids. It is derived from a partial sequence of human gastric juice protein and has been studied for its broad cytoprotective and healing properties.

How does BPC-157 work?

BPC-157 modulates the nitric oxide (NO) system, upregulates growth factor receptors, promotes angiogenesis, and has anti-inflammatory properties. It interacts with multiple biological pathways simultaneously.

How should BPC-157 be reconstituted?

Reconstitute with bacteriostatic water by gently injecting solvent along the vial wall. Allow to dissolve without shaking. Store reconstituted solution at 2-8°C and use within 14 days.

What makes BPC-157 different from TB-500?

While both promote tissue repair, BPC-157 is primarily cytoprotective with strong GI-healing properties, whereas TB-500 focuses on angiogenesis and cell migration. They work through different but complementary mechanisms.

  • Sources & References

Peer-reviewed publications and reference materials.

Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract

Sikiric P, et al.

Current Pharmaceutical Design (2018)

DOI: 10.2174/1381612823666171010151010

BPC-157 and its role in accelerating wound healing

Seiwerth S, et al.

Medical Science Monitor (2019)

DOI: 10.12659/MSM.915329

Pentadecapeptide BPC 157 and its effects on a NSAID toxicity model

Sikiric P, Rucman R, et al.

Life Sciences (2020)

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